Deeptech: A Lasting Trend Poised to Tackle the World's Most Complex Challenges

In this interview with Alexander Vaselek, CEO of Frankfurt-based early-stage start-up investor Cimedo Investment Group, we explore the evolving landscape of deeptech VC investments across Europe and the Mediterranean. With a growing ecosystem supported by government initiatives and private capital, this region is positioning itself as a key player in areas like AI, biotech, quantum computing, and robotics. While still trailing the U.S. in size and risk appetite, Europe is closing the gap by focusing on sustainability and long-term innovation. Our guest delves into the unique challenges facing deeptech startups, the sectors attracting the most investor attention, and what the future holds for this exciting field.

Alexander will be sharing the stage at the upcoming 0100 Conference Mediterranean in Milan in October at the “Deeptech Investments” panel, together with Maria Cristina Odasso at LIFTT, Stephan Wirries, Partner at Ventech, and Moritz Belling, Principal at Earlybird Venture Capital.

How would you describe the current state of deeptech VC investments in Europe and the Mediterranean region? How does it compare to developments in the US?

The deeptech investment landscape in Europe and the Mediterranean is really gaining momentum. Over the past few years, we’ve seen significant growth. That’s still smaller than the U.S., but the upward trend is clear.

One of the big drivers in Europe has been government support. Programs like Horizon Europe and national initiatives in countries like France and Germany are pouring funds into deeptech sectors, particularly those aligned with sustainability and societal impact, like clean energy and health tech. Southern Europe is still developing but showing potential.

When you compare this to the U.S., though, it’s a different ball game. The U.S. has a much larger deeptech ecosystem. U.S. investors also tend to take bigger risks at earlier stages, and the private sector (through corporate VCs and agencies like DARPA) plays a more dominant role. That leads to faster scaling and more exit opportunities, which is still a challenge in Europe.

Is it accurate to refer to deeptech as a trend? If so, do you think it's currently in the low end of the hype cycle?

I think it’s fair to call deeptech a trend, but it’s not a fleeting one, it’s here to stay. The promise of deeptech lies in its potential to solve some of the most complex global challenges, whether it’s climate change, healthcare, or energy. That said, deeptech does tend to have longer development cycles, which means that right now, many of the technologies are still in the early stages of the hype cycle. Investors are beginning to see the value, but because the timelines are long, there’s still a gap between the hype and actual widespread adoption. We’re at the stage where the foundational work is being laid, but it’s going to take a bit more time before we hit that peak of realization.

With deeptech often requiring longer timelines and more capital, what unique challenges do early-stage deeptech startups face, and how does Cimedo help them navigate these hurdles?

Early-stage deeptech startups face several unique challenges, primarily around funding and the extended time it takes to bring their innovations to market. Unlike other tech startups that can scale quickly, deeptech requires more patient capital and investors who understand that breakthroughs take time. These startups also often need to bridge the gap between scientific research and commercial viability, which can be a difficult balancing act.

At Cimedo, we focus on providing not just capital but also strategic support. We help startups by connecting them with industry experts, research institutions, and corporate partners, which is critical in deeptech. Additionally, we understand the long-term nature of deeptech development, so we offer flexible funding models and work closely with our portfolio companies to refine their go-to-market strategies. It’s about more than just money, it’s about giving them the ecosystem they need to succeed in the long run.

Which sectors within deeptech—such as AI, robotics, quantum computing, or biotech—are currently attracting the most attention from investors in Europe and the Mediterranean?

Right now, AI and biotech are definitely leading the way in Europe and the Mediterranean in terms of attracting investor interest. AI is being integrated across almost every sector, from healthcare to finance, which makes it a hot area for deeptech VCs. Biotech, especially in areas like genomics, personalized medicine, and drug discovery, is also seeing strong growth. Quantum computing is still in the earlier stages but is starting to attract attention as companies are making breakthroughs in hardware and applications. Robotics, particularly in industrial automation and healthcare, is another sector that’s gaining momentum, especially in key European markets like Germany and France.

How are the VC ecosystems in Europe and the Mediterranean evolving to support deeptech startups? What role do government initiatives and private funding play in fostering this growth?

The VC ecosystem in Europe and the Mediterranean is definitely evolving to better support deeptech. We’re seeing more specialized deeptech funds emerge, and generalist VCs are also starting to invest in deeptech because they see the potential for long-term returns. On top of that, government initiatives are playing a crucial role. The European Innovation Council, for example, is investing heavily in deeptech through grants and equity funding, which helps mitigate some of the risks that private investors might shy away from.

In southern Europe, while things are developing more slowly, we’re starting to see national governments and the EU funnel more resources into deeptech as they realize the strategic importance of these technologies. The collaboration between government funding and private capital is key to creating a robust environment where deeptech startups can thrive.

Looking ahead, what are your predictions for the future of deeptech VC investments in Europe and the Mediterranean? Are there specific trends or technologies you believe will drive the next wave of innovation?

I believe the future of deeptech VC investment in Europe and the Mediterranean is very promising. Over the next few years, we’re going to see more capital flowing into this space, especially as investors get more comfortable with the longer timelines and the potential for massive returns. AI and biotech will continue to dominate, but I also think sectors like quantum computing, green energy, and space technology will drive the next wave of innovation. Europe is putting a big focus on sustainability, so we’ll likely see a surge in investment around clean technologies, energy storage, and carbon capture.

Additionally, I expect to see more collaboration between governments and private investors, which will be crucial for scaling deeptech startups. As the ecosystem matures, Europe and the Mediterranean will play a leading role in developing technologies that address global challenges, and that will position the region as a key player in the deeptech world.

Blog

Other news you might be also interested in

Dealmaking Opportunities in the European Mid-Market Private Equity Landscape with Capital Dynamics

In this preview interview for the upcoming 0100 Conference Mediterranean, we had the privilege to speak with Andrea Mazzaferro, Head of Primaries at Capital Dynamics, who will participate in the opening panel: PE & VC Environment in Europe and the Mediterranean region: Current State & Future Perspectives. Andrea offers his expert insights on the evolving private equity and venture capital landscape, mid-market trends, and sector-specific opportunities. He also highlights the growing significance of ESG integration and Capital Dynamics’ forward-looking strategies for the region.

We’re Hiring: Head of Sales & Business Development (fully remote)

Join the Zero One Hundred Conference Team

We’re Hiring: Sales Executive (fully remote)

Join the Zero One Hundred Conference Team